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Direct photochemical degradation of extracellular enzymes

June 19, 2018

 

Christine Egli has a new paper in in Environmental Science & Technology on photochemically induced site-specific damage in aquatic extracellular enzymes. This work presents an optimized proteomics approach to study simultaneous inactivation and site-specific molecular changes in environmentally relevant model enzymes. We report site-specific degradation fingerprints in the three dimensional proteins and reveal subsequent intramolecular processes, such as antioxidant effects.

 

Proteomics Approach To Trace site-specific Damage in Aquatic Extracellular Enzymes During Photoinactivation

Christine M. Egli and Elisabeth M.-L. Janssen*

Environ. Sci. Technol.​ 2018 https://pubs.acs.org/doi/10.1021/acs.est.7b06439

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