Christine Egli has a new paper in in Environmental Science & Technology on photochemically induced site-specific damage in aquatic extracellular enzymes. This work presents an optimized proteomics approach to study simultaneous inactivation and site-specific molecular changes in environmentally relevant model enzymes. We report site-specific degradation fingerprints in the three dimensional proteins and reveal subsequent intramolecular processes, such as antioxidant effects.
Proteomics Approach To Trace site-specific Damage in Aquatic Extracellular Enzymes During Photoinactivation
Christine M. Egli and Elisabeth M.-L. Janssen*
Environ. Sci. Technol. 2018 https://pubs.acs.org/doi/10.1021/acs.est.7b06439